Expand your EHR’s AI capabilities with athenahealth Marketplace
In the modern healthcare ecosystem, it’s become imperative for practices to assess how well their core platform enables efficiency for clean data exchange and enhances specialty-specific workflows. In an age of growing AI adoption, that might include evaluating the merit of vendor solutions and whether bolted-on AI applications fragment data further or if the core platform is set up for seamless integration. With a cloud-based, single-instance SaaS, athenaOne® is built for seamless integration.
The Advanced Intelligence Layer in athenaOne and built-in AI capabilities can help reduce manual inputs across multiple workflows, from documentation assistance to routine automation. Growing organizations and specialty-focused practices may look for ways to further extend those capabilities.
Consider a multilocation practice managing complex population health initiatives, or an independent practice looking to automate patient outreach in ways that reflect their unique care philosophy. These scenarios often call for hyper-targeted solutions that complement athenaOne’s foundational capabilities and support highly granular needs in specific workflows.
The athenahealth Marketplace enables this extensibility by connecting practices with AI solutions designed for specific use cases. The Marketplace offers partner solutions across 70 digital health capabilities and 60 specialties1. Practices are finding value, as 71 percent of athenaOne customers use one or more partner solutions2.
Because Marketplace apps are designed to work within athenaOne’s existing framework, practices can layer in additional capabilities while preserving workflow continuity and platform consistency, without the typical integration headaches or workflow disruptions that can accompany new technology implementations.
Specialized AI solutions for unique practice needs
Numerous athenaOne customers have leveraged Marketplace AI integrations to solve complex operational challenges that standard workflows can’t address alone.
Take patient engagement automation. Posterity Health needed sophisticated outreach capabilities that could scale with their rapid growth in male fertility care. By integrating LeadSquared’s AI-powered CRM with athenaOne, they automated patient communications across email, text, and calls — achieving a 7X revenue increase and boosting conversion rates from 55% to 78%. The app handles timing, personalization, and follow-up sequences within the athenaOne ecosystem, enabling scale without fragmenting workflows.*
For revenue cycle optimization, TrustCare Health implemented Rivia Health’s payment engagement platform, which uses intelligent automation to identify optimal patient payment outreach timing and methods. The revenue cycle management (RCM) tool analyzes patient payment patterns and automatically sends personalized payment requests via the most effective channels. Result: 45% increase in patient payments and 389 hours saved monthly on manual collection tasks.**
Clinical monitoring gets smarter, too. Levine Heart & Wellness uses Accuhealth’s (now Tellihealth) remote patient monitoring solution with AI-driven alerts that analyze patient biometric patterns and flag concerning trends before they become emergencies. Their patients achieved -29 mmHg average reduction in systolic blood pressure, with the AI helping prevent an estimated $1.68 million in avoidable hospital visits.***
These success stories demonstrate how Marketplace AI solutions build on athenaOne’s core platform to deliver specialized automation and intelligence in three key areas: patient engagement, data interoperability, and clinical intelligence. Here’s how these capabilities work in practice.
AI-native athenaOne provides the foundation, and Marketplace apps extend its reach into specialized workflows, advanced analytics, and enhanced patient connections.
Patient engagement that scales with your practice
Marketplace apps can help deliver tailored engagement strategies that may deepen and personalize patient connections. That extends beyond patient digital engagement strategies that may include virtual front desks (patient portals), advanced telehealth platforms, and patient education modules.
For example, a cardiology clinic can use a Marketplace app to send personalized lifestyle tips after each visit. Patients feel supported between appointments, and medical professionals see better adherence to care plans and strategies. Integrated telehealth consolidates visits, notes, and follow-ups into a single workflow.
Adding Marketplace solutions can give practices the opportunity to customize patient outreach based on need state. That can help maximize targeted patient engagement while remaining seamlessly embedded within athenaOne’s existing communication framework.
Advanced interoperability and security solutions
Marketplace apps extend athenaOne’s interoperability foundation with specialized integrations tailored to specific clinical and operational strategies.
Clinicians can enhance interoperability with Marketplace apps that integrate with imaging systems, lab networks, or specialty registries. athenaOne’s security model carries over to these apps as well. Security stays consistent across both platform and Marketplace tools, with compliance and data protection built into every layer. Practices can move beyond basic data exchange to targeted interoperability strategies that support research, specialty care, and advanced coordination.
Oncology practices, for example, may use registries to manage clinical trials. A Marketplace app connects directly to trial databases while maintaining full security and compliance. The practice gains a competitive edge in research participation within the framework of athenaOne’s secure infrastructure.
Nexus-MD offers all-in-one imaging workflow integration directly within athenaOne. For clinical research, Trially connects practices to trial databases, enabling seamless patient matching and enrollment tracking.
Clinical Intelligence and AI-Powered Insights
Marketplace apps bring specialized clinical intelligence that builds on athenaOne’s analytics and reporting capabilities to deliver deeper, specialty-specific insight.
Clinical teams can access AI-powered insights for specific specialties or conditions that standard EHR reporting can’t always provide. These apps analyze patient data patterns, predict risk factors, and suggest evidence-based interventions. The intelligence stays within athenaOne’s secure environment while providing actionable insights that improve patient outcomes.
Consider a primary care practice managing patients with diabetes. A clinical intelligence app identifies patients at risk for complications before symptoms appear. The app suggests preventive interventions and tracks outcomes over time. The practice improves patient health while reducing costly emergency interventions, leveraging athenaOne’s centralized data as the operational foundation].
Rounding out the Marketplace contribution
AI-native athenaOne provides the foundation, and Marketplace apps extend its reach into specialized workflows, advanced analytics, and enhanced patient connections. Together, they create a healthcare ecosystem that adapts to practice needs without disrupting core workflows or requiring system overhauls.
Practices can layer Marketplace apps onto athenaOne’s core capabilities to build the system they need. A cardiology practice can add specialized imaging integration. A family medicine group can incorporate patient engagement tools. An oncology practice can connect to clinical trial databases. Each choice strengthens the practice’s competitive position and helps maintain a unified platform experience.
The future belongs to platforms that help practices scale and innovate without disruption. Marketplace apps allow practices to stay agile, adapting to emerging needs of clinicians and patients alike. The combination delivers both reliability and flexibility.
Visit the athenahealth Marketplace to explore solutions for your unique practice needs.
- Based on athenahealth data as of Dec. 2025; M029
- Based on athenahealth data as of Dec. 2025; M030
* Results may vary by provider. Please note that as a member of the Marketplace Program, LeadSquared and athenahealth are parties to a financial arrangement.
** All metrics provided by Rivia Health. Please note that as a member of the Marketplace Program, Rivia Health and athenahealth are parties to a financial arrangement.
*** These results reflect the experience of one particular organization and are not necessarily what every athenahealth customer should expect.




